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POTS and Fatigue: A Primary Care Approach to Evaluation and Management

OSUPCO Mentorship Program Case Discussion Series

Friday, September 4, 2026 at 11:30 AM

This grand round has already taken place.

Online Streaming
September 4th, 2026
1.00 AMA PRA Category 1 Credit™ Hours

Description

Fatigue and orthostatic symptoms are common yet often challenging complaints encountered in primary care. This case-based discussion will review the evaluation of a young adult presenting with chronic fatigue, orthostatic intolerance, palpitations, and cognitive symptoms ultimately consistent with Postural Orthostatic Tachycardia Syndrome (POTS). Participants will explore the differential diagnosis of fatigue and orthostatic tachycardia, appropriate diagnostic workup, interpretation of orthostatic vital signs, and evidence-based management strategies. Through interactive discussion, attendees will gain practical tools to recognize POTS, identify red flags requiring referral, and implement effective nonpharmacologic and pharmacologic treatment approaches.

Dates and Times

Start: 9/4/2026 11:30 AM
End: 9/4/2026 12:00 PM

Objectives

At the conclusion of this activity, participants will be able to:

  1. Develop an evidence-based differential diagnosis for patients presenting with chronic fatigue, orthostatic symptoms, and tachycardia in the primary care setting. 
  2. Interpret orthostatic vital signs and clinical findings to distinguish POTS from other causes of orthostatic intolerance, syncope, and sinus tachycardia.
  3. Implement appropriate diagnostic evaluation and referral strategies for patients with suspected POTS, including identification of red flag features requiring specialty consultation. 
  4. Apply current evidence-based treatment recommendations for POTS, including lifestyle interventions, exercise therapy, volume expansion, compression therapy, and pharmacologic options when indicated. 
  5. Incorporate a structured approach to evaluating fatigue that balances identification of underlying medical conditions while avoiding unnecessary diagnostic testing.

Speakers

  • Allen Frye, APRN
    • POTS and Fatigue

Accreditation Statement

The Ohio State University is accredited by the Accreditation Council for Continuing Medical Education (ACCME®) to provide continuing medical education for physicians.

AMA Credit Designation Statement

The Ohio State University designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) ™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Need help with this Grand Round Session?

Please contact the Grand Round coordinator listed below:

Deanna Smith
Email: Deanna.Smith@osumc.edu